The gdx laser diagnostic technologies, san diego, ca is a scanning laser polarimeter that measures retardation to assess retinal nerve fiber layer thickness. Optic nerve and retinal nerve fiber imaging eyewiki. Optical coherence tomography and scanning laser polarimetry slp are the techniques that utilize the. Scanning laser polarimetry slp is a confocal scanning laser ophthalmoscope with an integrated polarimeter that measures the amount of retardation phase shift of a polarized nearinfrared laser beam as it passes through the rnfl. Scanning laser polarimetry images were obtained using a commercial gdx vcc system version 5. Retinal scanning, scanning laser ophthalmoscopy, optical coherence tomography, oct, scanning laser polarimetry. We describe the application of a scanning laser polarimeter for quantitative measurements of the retinal nerve fiber layer thickness in vivo.
This technology grew out of efforts to improve scanning laser ophthalmoscopy. Scanning laser polarimetry an overview sciencedirect. Scanning laser polarimetry slp utilizes a scanning laser ophthalmoscope to determine the peripapillary rnfl thickness, pixel by pixel, by measuring the total retardation of polarized light reflected from the. The free public glaucoma screening available over a period of 4 d was. Scanning laser polarimetry and progression of visual field. Stepper motors were incorporated into a cslo to semiautomate mueller matrix polarimetry. Aim to evaluate the applicability of imaging devices spectraldomain optical coherence tomography cirrus sdoct, scanning laser polarimetry gdx and scanning laser ophthalmoscopy. This technology grew out of efforts to improve scanning laser. To determine the correlations and strength of association between different imaging systems in analyzing the retinal nerve fiber layer rnfl of glaucoma patients. Scanning laser polarimetry slp, a technology for glaucoma diagnosis, uses. Technology today the nerve fiber layer and scanning laser. Purpose to compare the usefulness in glaucoma screening of scanning laser. After the intraocular pressure increase, there were changes in scanning laser polarimetry results and progression of visual field defects at standard a chromatic automated perimetry. Optical coherence tomography, scanning laser polarimetry.
Accuracy of scanning laser polarimetry, scanning laser tomog. Methodsretinal nerve fibre layer thickness was measured with a scanning laser. Scanning laser polarimetry in normal subjects and patients. Many studies have been done on variation of nfl thickness measurements with age and ethnicity by scanning laser polarimetry,912 but the effect of refractive changes on nfl thickness measurements with the scanning laser polarimeter is. Kupersmith,1 randy kardon,2 mary durbin,3 melissa horne,3 and julia shulman4. Scanning laser polarimetry slp is a confocal scanning laser ophthalmoscope with an integrated polarimeter that measures the amount of retardation phase shift of a polarized nearinfrared laser. While white light scatters in ocular media, the use of. Relationship between scanning laser polarimetry with.
Axonal loss from acute optic neuropathy documented by. Scanning laser polarimetry slp is a technique designed to evaluate the rnfl based on the. Detection of glaucoma with scanning laser polarimetry glaucoma. Scanning laser polarimetry definition of scanning laser. Scanning laser polarimetry is the use of polarised light to measure the thickness of the retinal. These are confocal scanning laser ophthalmoscopy, optical coherence tomography and scanning laser polarimetry.
Hence, the measurement of rnfl thickness has come up. Scanning laser polarimetry may have good sensitivity and specificity for separating normal from abnormal eyes, but it is not as good for classifying unknown subjects when glaucoma suspects are. Diagnostic performance of modern imaging instruments in. Scanning laser ophthalmoscopy slo is a method of examination of the eye. Aims to evaluate the clinical value of scanning laser polarimetry with the nerve fibre analyser type ii in primary open angle glaucoma poag and capsular glaucoma. Objective to compare retinal nerve fiber layer rnfl measurements obtained withscanning laser polarimetry slp using variable corneal polarization compensationwith standard red free. Though the technology has been available for several years, recent advances have. Scanning laser polarimetry using the gdx vcc offers a unique tool for imaging of rnfl changes in glaucoma. Pdf comparison of scanning laser polarimetry using variable. Scanning laser polarimetry quantification of retinal nerve. A total of 179 eyes from 82 normal subjects and 97 glaucoma patients. Detection of glaucoma using scanning laser polarimetry with.
Aimsto examine the changes in the retinal nerve fibre layer nfl thickness with age and myopia in normal population. Modern technologies for retinal scanning and imaging. Compared to a previous study using red free photographs, scanning laser polarimetry showed retinal nerve fibre layer loss earlier in the course of descending atrophy. Scanning laser polarimetry slp is an imaging technology designed to provide. Scanning laser polarimetry is a technique for assessing the thickness of the retinal nerve fiber layer in vivo. In addition to standard automated perimetry, gonioscopy, fundus photography, and stereophotography, other advanced, highresolution methods for imaging the eye in glaucoma are explained in detail, including ultrasound biomicroscopy, confocal scanning laser ophthalmoscopy, scanning laser polarimetry. Scanning laser polarimetry slp is a new image analysis technique which uses the polarising properties of the retinal nerve fibre layer rnfl to produce a quantitative measure of its. Analytical methods for scanning laser polarimetry osa. It uses the technique of confocal laser scanning microscopy for diagnostic imaging of retina or cornea of the human eye as a.
Scanning laser polarimetry reveals status of rnfl integrity in eyes with optic nerve head swelling by oct mark j. All subjects had full ophthalmologic evaluation with stereophotography of the optic nerve head onh, red free retinal nerve fiber layer rnfl photography, scanning laser polarimetry. Diagnostic accuracy of glaucoma tests in everyday practice. Pdf scanning laser polarimetry in eyes with exfoliation. Subjects referred because of suspicion of glaucoma were recruited. Scanning laser polarimetry is a diagnostic method that has been developed to measure quantitatively the thickness of the peripapillary retinal nerve fiber layer rnfl. Variation of nerve fibre layer thickness measurements with age and ethnicity by scanning laser polarimetry. The total macular volume for the patient in a is 7. Motion artifacts in scanning laser polarimetry ophthalmology. Scanning laser topography and scanning laser polarimetry the open ophthalmology journal, 2012, volume 6 7 compensation ecc, is said to have further improved the evaluation of the rnfl by the. The main birefringent intraocular tissues are the cornea, lens and the retina.
Comparison of scanning laser polarimetry using variable. Scanning laser polarimetry slp is a technique that uses the polarization properties of light to measure the phase retardation induced by the birefringence of the rnfl. Measurement of the retinal nerve fibre layer with scanning. Scanning laser polarimetry is the use of polarised light to measure the thickness of the retinal nerve fiber layer as part of a glaucoma workup. Scanning laser polarimetry in glaucoma t anuj dada, reetika sharma, dewang angmo, gautam sinha, shibal bhartiy a, sanjay k mishra, anita panda, ramanjit sihota. Scanning laser polarimetry was developed at the university of california, san diego, and introduced as a commercial instrument by laser diagnostic technologies san diego, ca. To evaluate the ability of scanning laser polarimetry with variable corneal compensation to detect progressive retinal nerve fiber layer rnfl loss in glaucoma patients and patients suspected of having.
Objectiveto determine which retinal nerve fiber layer rnfl measures obtained with scanning laser polarimetry are most useful in detecting early to moderate. Comparison of scanning laser polarimetry using variable corneal compensation. Detection of glaucoma with scanning laser polarimetry. Gps provides glaucoma classification without the need for manual outlining of the. Evaluation of retinal nerve fiber layer using scanning laser polarimetry article pdf available september 2010 with 776 reads how we measure reads. Scanning laser polarimetry versus matrix perimetry, optical coherence tomography, and retinal nerve fiber layer photography using heidelberg retina angiograph 1. Introducing nideks f10, a confocal scanning laser ophthalmoscope that brings a significant advancement in imaging of the retina. Scanning laser polarimetry slp reveals abnormal retardance of birefringence in locations of the edematous peripapillary retinal nerve fiber layer rnfl, which appear thickened by.
Confocal scanning laser ophthalmoscopy, optical coherence tomography, and polarizationsensitive retinal scanning. Predictors of atypical birefringence pattern in scanning. Several studies with optical coherence tomography oct have demonstrated thinning of the retinal nerve fiber layer rnfl in patients with optic neuritis and multiple sclerosis. This study aimed to compare scanning laser polarimetry measurements of retinal nerve fibre layer rnfl thickness in eyes of migraine patients with those in eyes of agematched, healthy subjects. An increase in superior and inferior nerve fiber loss was observed with scanning laser polarimetry.
Aims scanning laser polarimetry is a new technique allowing quantitative analysis of the retinal nerve fibre layer in vivo. Retinal imaging by laser polarimetry and optical coherence. An observation of unusual retinal patterns under certain optical condi. In the 1990s, three new technologies were introduced for optic nerve imaging which garnered significant interest. Background optical coherence tomography oct and scanning laser polarimetry with variable corneal compensation gdx are similar yet provide information on different aspects of retinal. Scanning laser polarimetry, but not optical coherence. Scanning laser polarimetry of the retinal nerve fibre. Often expensive and complicated, these techiques failed to reach the level of common use. To evaluate predictors of atypical birefringence patterns abp observed in scanning laser polarimetry. Scanning laser polarimetry an overview sciencedirect topics.
Open access scanning laser topography and scanning laser. The measuring beam of the scanning laser polarimeter is focused. Scanning laser polarimetry of the retinal nerve fiber layer. Scanning laser polarimetry in eyes with exfoliation syndrome article pdf available in european journal of ophthalmology 235 march 20 with 35 reads how we measure reads. Scanning laser polarimetry is an imaging technology that is utilized to measure peripapillary rnfl thickness. The traditional clinical examination of the retinal nerve fibre layer involves redfree ophthalmoscopy and photography.
Scanning laser polarimetry with variable and enhanced. Pdf early diagnosis of glaucoma requires evaluation of the retinal nerve fiber layer rnfl to. Distributionfree roc analysis using binary regression techniques. Pdf to compare retinal nerve fiber layer rnfl measurements obtained with scanning laser. Pdf evaluation of retinal nerve fiber layer using scanning laser.
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